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PUBLIKATIONEN

Unsere Publikationen

Unsere Forschung richtet sich neben weiteren Fach­gebieten vor allem auf den menschlichen Bewegungs­apparat mit Fokus auf Gewebe­regene­ration und Implantaten. Zusätzlich fokussieren wir uns auf die Herstellung, Bearbeitung und Charakte­risierung von Werk­stoffen und Ober­flächen. Die Resultate aus unserer Forschungs­tätigkeit publizieren wir in international anerkannten Fachzeitschriften.

Hier finden Sie die Auflistung von Publikationen mit Beteiligung der RMS Foundation nach Jahr ihrer Erscheinung.

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    Publikationen 2024

    The reactivity of α-tricalcium phosphate powders is affected by minute amounts of β-calcium pyrophosphate and by the synthesis temperature

    Marc Bohner, Fabrizio Bigolin, Isabelle Bohner, Thomas Imwinkelried, Yassine Maazouz, Pascal Michel, Christoph Stähli, Yves Viecelli, Nicola Döbelin
    Open Ceramics, Volume 19, September 2024, 100647
    Abstract

    α-tricalcium phosphate (α-TCP) is the most widespread raw material for hydraulic calcium phosphate cements (CPCs). CPCs are widely used in bone repair due to their injectability, setting ability, and osteoconductivity. This study investigated the reactivity of α-TCP powders, focusing on the impact of minor phase impurities, β-calcium pyrophosphate and hydroxyapatite, and the synthesis temperature. The α-TCP powders were synthesized via a solid-state reaction of calcium carbonate and anhydrous dicalcium phosphate, with varying Ca/P molar ratios (1.4850–1.5075) and synthesis temperatures (1175°C–1350 °C). Powders produced with a Ca/P molar ratio below 1.50 and synthesized at a temperature above the melting point of β-CPP (1296 °C) had a broader size distribution and a two to fourfold lower hydraulic reactivity. Conversely, a higher Ca/P molar ratio improved reactivity. The study underscores the importance of precise control over synthesis parameters to enhance the performance of α-TCP-based CPCs, offering insights for optimizing material design in biomedical applications.